Researchers at Cambridge University carried out more than 117,000 experiments on animals last year.
Animals used included 103,580 mice, 35 monkeys and three horses. It was also revealed yesterday that 2,000 out of the 117,212 experiments were classed as the highest level of severity.
Animal rights campaigners reacted with fury at the figures, released under the Freedom of Information Act.
Andrew Tyler of Animal Aid said: "These animals are not reliable surrogates for human beings and we don't have the moral authority to inflict such torments.