News Index > Sortable News 10/06 - now > October '07
Cats-On-Meth Begins Again at The Ohio State University
Since 2002, following the departure of Michael Podell, OSU, NIH, and Lawrence Mathes seemed to have not been using cats for the infamous Cats-On-Meth protocol.
While NIH continued to fund the grant, because they didn't want animal activists to think they had won on the issue, OSU and Mathes, the new PI, seemed to indicate that cats would NOT be used.
Podell's original plan was to infect up to 120 cats with FIV -- feline immunodeficiency virus, which is an animal model for HIV in humans -- and then addict the cats to methamphetamines to see how the drugs affected the progression of the disease in the brain.
So far, 42 cats have been killed to study brain changes, Mathes said.
But, at least for the next year, no cats will be used because the focus now is on analyzing tissue from those already euthanized and testing viral response to drugs in cell cultures. The cultures, which Ohio State purchases, were cloned from skin or tumor cells from live or dead cats. Using them is one way to reduce the number of live animals required.
And from The Lantern
Holland said the research no longer involves the testing of animals.
"We are not using cats in our research at this point in time or in the foreseeable future. The research has shifted to conventional, basic tissue culture work. No animals are being harmed," Holland said.
The NIH grant expired May 31, 2006. P.O.E.T. using NIH search engine pubmed, could find no additional published works above what Podell/Mathes published in 2002.
August 23, 2007 - The OSU IACUC approve the use of 24 cats to conduct a prospective study to establish that methamphetamine accelerates the development of AZT resistance in FIV infected cats.
September15, 2007 - An NIH grant from The National Institute on Drug Abuse begins for a project entitled: Do Psychostimulatory Drugs Enhance Lentivirus Infection?
Specific Aim #2 is designed to test the hypothesis in vivo via a proof-of-principle study in the FIV/cat system to evaluate the effect of METH on the development of AZT resistance in vivo.
E. Gordon Gee, President of The Ohio State University
Stop the funding contact your US House representative. A list can be found at http://www.house.gov/ .
For background information on the Cats-On-Meth experiments click the following link:
Demonstrations are in the works with the first demonstration being scheduled for:
Thursday, October 11th
More information to follow.