Perhaps; but these differences of means are substantial. Most Buddhists would challenge the idea that technology offers an escape-route from the pain of earthly existence. Despite the cumulative success stories of scientific medicine, it would seem the advances of modern technology haven't left human beings any happier on average than our ancestors on the African savannah. Indeed the incidence of clinical depression, anxiety disorders, suicide, drug abuse, marital breakdown and other "objective" indices of distress is rising in Western consumer capitalist society as a whole. The track-record of technological science to date is not encouraging. Opponents of scientific utopianism envisage that its application will yield - at best - some type of "Brave New World".

Abolitionists respond that only biotechnology can ever deliver the world from suffering. Unless the biological substrates of unpleasantness are eradicated, then suffering is genetically preordained. All Darwinian humans periodically go through periods of distress ["dukkha"]; its intensity and duration varies, but its spectre is never absent. Endowing their vehicles with a capacity to suffer enhanced the inclusive fitness of our genes in the ancestral environment. A heritable capacity to undergo all sorts of nasty states, conditionally activated, has been genetically adaptive. Sadly, even devout Buddhists undergo pain, sorrow and malaise in the course of their lives. A Buddhist lifestyle and meditational disciplines may offer palliative relief. Yet given a Darwinian genome, no pursuit of a "Noble Eight-fold Path" can re-set our emotional thermostats, redesign our gene expression profiles, or dismantle the "hedonic treadmill" of Darwinian life. In evolutionary history, primate mothers who weren't anxiety-ridden, "attached" to their children, and desirous of their success left less copies of their genes than their malaise-ridden, un-Buddhist-like counterparts.

Moreover, with a traditional neural architecture, it's notable that desire-driven "hyper-dopaminergic" people, who have the greatest range and intensity of appetites, tend to be the least unhappy - though their lives can still be blighted by disappointment and loss. By contrast, the extinction of desire experienced by many contemporary humans is more akin to apathy and withdrawal than illumination - not enlightenment and consequent nirvana but instead a condition of melancholia or anhedonia: emptiness in the sense of an absence of meaning. This isn't the kind of extinction of desire Buddhists have in mind; but it's unclear if Buddhism offers a solution to, say, anhedonia - the incapacity to feel happiness or anticipate reward - characteristic of many depressives.

Looking to the future, the new technologies of post-genomic healthcare promise effectively unlimited joy, meaning and motivation - or serenity. If we so desire, a rich hyper-spirituality can be awakened, too, even in the otherwise spiritually barren. Intelligence can be pharmacologically and genetically amplified, as can lifespans, perhaps indefinitely; and also, more counter-intuitively, compassion. In future, genetic engineering will allow control over archaic emotions and eventually the creation of whole new categories of experience in state-spaces of consciousness hitherto unknown.

More prosaically, but more importantly from an ethical point of view, the reproductive revolution of "designer babies" will enable us to choose how much - or how little - suffering we bring into the world when we decide the genetic-make-up of our children. Gradients of genetically pre-programmed well-being can be the destiny of our offspring from conception, depending on which dial-settings we favour. If we so choose, we can abolish the soul-polluting nastiness of Darwinian life altogether. Dukkha can be consigned to historical oblivion; and replaced by a post-Darwinian era of mental superhealth.

The era of mature genomic medicine is still decades away, perhaps longer. Buddhists are surely right to stress how desire and attachment as experienced today often lead to heartbreak. But when heartbreak becomes genetically impossible, it will be safe to follow one's heart's desire without limit. More generally, an absence of desire is a recipe for personal and social stagnation, whereas an abundance of desires is a precondition of intellectual dynamism and social progress.

Even so, control over our emotions strikes many bioconservatives as a frightening prospect, evoking images of enslavement rather than empowerment. It's worth recalling how some early commentators feared that the discovery of anaesthesia gave doctors too much power over their patients; the use of anaesthetics for painless surgery allegedly robbed the individual of his or her autonomy and the capacity to act as a rational agent, reducing the patient "to a corpse". In a contemporary context, investing a quasi-priestly caste of physicians with the sole lawful power to grant - or withhold - pleasure-giving, pain-relieving drugs undoubtedly does magnify the scope for abuses of authority.

Whatever the risks, technologies of pain-eradication are too valuable to renounce, even if this option were sociologically realistic. Right now, of course, the vision of life without suffering still strikes many non-Buddhists and even Buddhists as fanciful. Life-long happiness seems no more likely than the prospect of effective "pain killers" or pain-free surgery struck our early Victorian forebears. We are possessed by the deep unspoken feeling that "what has always been was always meant to be". Even classical utilitarians may find it difficult to believe that suffering could be eradicated in the foreseeable future in the same way as, say, smallpox. Yet it is hard to underestimate just how radical will be the effects of rewriting the vertebrate genome as the millennium unfolds. The abolition of the biological substrates of suffering promises to mark a major discontinuity in the development of life on earth. Our genetically enriched descendants may regard existence without "dukkha" - the abolition of suffering - as the ethical foundation of any civilised society.